{ "_id": "6ad86c9269e274306bae924e", "Package": "pksensi", "Title": "Global Sensitivity Analysis in Physiologically Based Kinetic\nModeling", "Version": "1.4.0.9000", "Authors@R": "c(\nperson(given = \"Nan-Hung\",\nfamily = \"Hsieh\",\nrole = c(\"aut\", \"cre\"),\nemail = \"d99622005@ntu.edu.tw\",\ncomment = c(ORCID = \"0000-0003-0163-2766\")),\nperson(given = \"Brad\",\nfamily = \"Reisfeld\",\nrole = \"ctb\",\ncomment = c(ORCID = \"0000-0003-1310-1495\")),\nperson(given = \"Weihsueh A.\",\nfamily = \"Chiu\",\nrole = \"ctb\",\ncomment = c(ORCID = \"0000-0002-7575-2368\")))", "Description": "Applying the global sensitivity analysis workflow to\ninvestigate the parameter uncertainty and sensitivity in\nphysiologically based kinetic (PK) models, especially the\nphysiologically based pharmacokinetic/toxicokinetic model with\nmultivariate outputs. The package also provides some functions\nto check the convergence and sensitivity of model parameters.\nThe workflow was first mentioned in Hsieh et al., (2018)\n, then further refined (Hsieh et\nal., 2020 ).", "License": "GPL-3 | file LICENSE", "URL": "https://github.com/nanhung/pksensi,\nhttps://nanhung.github.io/pksensi/", "BugReports": "https://github.com/nanhung/pksensi/issues", "VignetteBuilder": "knitr", "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "7.3.2", "Language": "en-US", "Roxygen": "list(markdown = TRUE)", "Repository": "https://nanhung.r-universe.dev", "Date/Publication": "2024-11-27 17:31:55 UTC", "RemoteUrl": "https://github.com/nanhung/pksensi", "RemoteRef": "HEAD", "RemoteSha": "a775203eab90fa09059fde7190396d730ae04351", "NeedsCompilation": "no", "Packaged": { "Date": "2026-10-21 07:37:12 UTC", "User": "root" }, "Author": "Nan-Hung Hsieh [aut, cre] (ORCID:\n),\nBrad Reisfeld [ctb] (ORCID: ),\nWeihsueh A. 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