Package: pksensi
Title: Global Sensitivity Analysis in Physiologically Based Kinetic
        Modeling
Version: 1.4.0.9000
Authors@R: c(
      person(given = "Nan-Hung", 
             family = "Hsieh", 
             role = c("aut", "cre"),
             email = "d99622005@ntu.edu.tw",
             comment = c(ORCID = "0000-0003-0163-2766")),
      person(given = "Brad", 
             family = "Reisfeld",
             role = "ctb", 
             comment = c(ORCID = "0000-0003-1310-1495")),
      person(given = "Weihsueh A.", 
             family =  "Chiu", 
             role = "ctb", 
             comment = c(ORCID = "0000-0002-7575-2368")))
Description: Applying the global sensitivity analysis workflow to
        investigate the parameter uncertainty and sensitivity in
        physiologically based kinetic (PK) models, especially the
        physiologically based pharmacokinetic/toxicokinetic model with
        multivariate outputs. The package also provides some functions
        to check the convergence and sensitivity of model parameters.
        The workflow was first mentioned in Hsieh et al., (2018)
        <doi:10.3389/fphar.2018.00588>, then further refined (Hsieh et
        al., 2020 <doi:10.1016/j.softx.2020.100609>).
License: GPL-3 | file LICENSE
URL: https://github.com/nanhung/pksensi,
        https://nanhung.github.io/pksensi/
BugReports: https://github.com/nanhung/pksensi/issues
Depends: R (>= 4.1)
Imports: ggplot2, data.table, deSolve, foreach, parallel, doParallel
Suggests: covr, knitr, httk, rmarkdown, testthat
VignetteBuilder: knitr
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.2
Language: en-US
Roxygen: list(markdown = TRUE)
Repository: https://nanhung.r-universe.dev
Date/Publication: 2024-11-27 17:31:55 UTC
RemoteUrl: https://github.com/nanhung/pksensi
RemoteRef: HEAD
RemoteSha: a775203eab90fa09059fde7190396d730ae04351
NeedsCompilation: no
Packaged: 2026-06-23 08:00:15 UTC; root
Author: Nan-Hung Hsieh [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-0163-2766>),
  Brad Reisfeld [ctb] (ORCID: <https://orcid.org/0000-0003-1310-1495>),
  Weihsueh A. Chiu [ctb] (ORCID: <https://orcid.org/0000-0002-7575-2368>)
Maintainer: Nan-Hung Hsieh <d99622005@ntu.edu.tw>